Physicians dealing with hypertension soon face the fact that blood pressure measurement on the upper arm only provides indirect information about the arterial status and about the deeper, more complex vascular changes. During our daily work, assessing the patient’s status anddeciding on the treatment, parameters describing arterial function (stiffness) are not available unfortunately, due to the lack of an adequate measuring option. Although we all aware that the blood pressure measured on the upper arm and on the aorta are significantly different, we also learned in the physiology that the pulse pressure wave generated by the left ventricle runs through the aorta and is reflected from the bifurcation, we also know that if the aortic wallis stiffened, the Pulse Wave Velocity (PWV) accelerates, however we did not have ease of use, everyday method to measure all these routinely. The only (invasive) way to get this data was through cardiac catheterization. On the other hand with the technical development we started to see the first non-invasive solutions (the applanation tonometry and the piezoelectric method), the application of these was complicated; it required a well-trained staff and the measurement took considerably long time. For these reasons, these solutions could not spread across the clinical field. How the story started? On one occasion, together with my development engineer colleagues, we had an opportunity to watch the signals on an oscilloscope during a digital, oscillometric blood pressure measurement. It was surprising to see how complex and at the same time distinct signals can be observed in the different pressure areas of the cuff. From this moment, we were eager to find out why only the maximum amplitudes are used from the oscillometric readings (to determine the blood pressure) and why do not we study the whole reading with all it’s details. We were assuming that the oscillometric readings might be consisting direct information about the state of the arteries and the systemic circulation. Examining our hypothesis, we started to research the scientific studies, articles and patents in this field but could not find any. It has become clear that we identified an area which has been rarely studied (or not at all) so we began to look for a way to start our own research.